Artificial Intelligence Enabled Zero-Trust Cyber Security Framework for Smart Healthcare Infrastructure

Authors

  • Dr.P. Selvaperumal Assistant Professor, Department of Computer Science, St Joseph's University, Bengaluru, India.
  • Dr. Lulup Kumar Sahoo Professor, Department of Neurology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.
  • Arjit Tomar Department of Computer Science & Engineering,Noida international University, Greater Noida, Uttar Pradesh 203201, India.
  • Kiran Ingale Assistant Professor, Department of E&TC Engineering, Vishwakarma Institute of Technology, Pune, Maharashtra, 411037.
  • Nainavarapu Radha Associate Professor, Department of ECE, Aditya University, Surampalem, Andhra Pradesh, 533437.
  • Dr. Devanshu J. Patel Associate Professor, Department of Pharmacology, Parul University, PO Limda, Tal. Waghodia, District Vadodara, Gujarat, India.
  • Dr. Shikhar Verma Professor , MSOPS, Maharishi University of Information Technology, Lucknow, Uttar Pradesh, India.
  • Harshini R Computer Science, Assistant Professor, Meenakshi College of Arts and Science, Meenakshi Academy of Higher Education and Research , Chennai, Tamil Nadu, India.

Keywords:

Zero-Trust Security, Smart Healthcare, Artificial Intelligence, Cybersecurity Framework, Intrusion Detection, IoMT Security

Abstract

Smart infrastructure deployment in healthcare, such as the Internet of Medical Things (IoMT) devices, cloud-based clinical platforms and intelligent patient monitoring systems, has greatly enhanced the vulnerabilities of the healthcare infrastructure. Traditional perimeter security solutions are not enough to defend against advanced attacks like ransomware, unauthorised access, data breaches or insider threats. These challenges led to proposing an AI-enabled Zero-Trust Cyber Security Framework for smart healthcare infrastructure that continuously verifies the users, devices, and network activities before providing access to critical medical resources. The plan in the proposed infrastructure is to combine Zero-Trust Architecture (ZTA) principles with an AI-based threat detection system that can detect unusual behavior and patterns of malicious traffic in real time. An adaptive intrusion detection, dynamic trust evaluation and intelligent access control are implemented with the help of a hybrid deep learning model. The experimental validation has been performed on cybersecurity datasets related to the healthcare industry and simulated smart healthcare traffic scenarios. The proposed framework achieves high results for attack detection accuracy, low false positive and low authentication latency compared to the conventional security techniques, as shown by results. The framework improves security resilience, scalability and instant protection for the next generation smart healthcare ecosystems.

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Published

2026-05-12

How to Cite

Selvaperumal, D., Sahoo, D. L. K., Tomar, A., Ingale, K., Radha, N., Patel, D. D. J., … R, H. (2026). Artificial Intelligence Enabled Zero-Trust Cyber Security Framework for Smart Healthcare Infrastructure. International Journal of Artificial Intelligence and Machine Learning, 6(2s), 204–217. Retrieved from https://svedbergopen.com/index.php/ijaiml/article/view/198

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